PGD2 inhibitor 1 - Names and Identifiers
PGD2 inhibitor 1 - Physico-chemical Properties
Molecular Formula | C23H23Cl2N3O3
|
Molar Mass | 460.35 |
Density | 1.326±0.06 g/cm3(Predicted) |
Boling Point | 682.1±65.0 °C(Predicted) |
Solubility | DMSO: ≥ 25 mg/mL |
pKa | 4.09±0.10(Predicted) |
Storage Condition | -20℃ |
In vitro study | Prostaglandin D2 (PGD2) is a major inflammatory mediator implicated in asthma and allergic rhinitis. It is largely produced as the major cyclooxygenase metabolite upon allergen-provoked degranulation from mast cells. Blockage of PGD2 using DP antagonists has been shown to be effective at alleviating the symptoms of allergic rhinitis in multiple species and more specifically has been shown to inhibit the antigen-induced nasal congestion. |
PGD2 inhibitor 1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.172 ml | 10.861 ml | 21.722 ml |
5 mM | 0.434 ml | 2.172 ml | 4.344 ml |
10 mM | 0.217 ml | 1.086 ml | 2.172 ml |
5 mM | 0.043 ml | 0.217 ml | 0.434 ml |
Last Update:2024-01-02 23:10:35